The molecular basis of sex and differentiation: a comparative study of evolution, mechanism, and control in microorganisms. …

216 S. Das hier angebotene Buch stammt aus einer teilaufgelösten wissenschaftlichen Bibliothek und trägt die entsprechenden Kennzeichnungen (Rückenschild, Instituts-Stempel...). Der Buchzustand ist ansonsten ordentlich und dem Alter entsprechend gut. CHAPTER 1 Embryology and the Study of Microbial Development CHAPTER 2 Molecular Events Accompanying Morphogenesis 10 Cell-Cycle Dependent Morphogenesis in Caulobacter 11 Control of Vegetative Morphogenesis in Neurospora 13 Ion Currents Associated with Morphogenesis in Brown Algae 17 The Generation and Roles of Ion Currents in Development 20 Selected References 22 CHAPTER 3 Cellular Mortality, Growth Regulation, and the Phenomenon of Cancerous Transformation 24 Evolution of Multicellularity 25 Two Fundamental Types of Cancerous Transformation 27 Teratocarcinogenesis—Reversible Malignancy 28 Transformation of Normal Somatic Cells 33 Selected References 36 CHAPTER 4 Sporulation in Evolutionary Divergent Prokaryotes and Eukaryotes 38 Sporulation in Bacillus 39 Bacterial Endospore Germination 45 Ascospore Formation in Yeast 46 Conidiation in Streptomyces and Neurospora 48 Fruiting in Myxobacteria and Dictyostelium 53 Selected References 58 CHAPTER 5 Control of Spatial Differentiation by Chemical Morphogens 60 Spatial Control of Fruiting Body Formation in Dictyostelium 61 Heterocyst Development in Blue-Green Bacteria (Anabaena) 65 The Temporal Program for Heterocyst Formation 66 /850135923xiv Contents Spatial Regulation of Heterocyst Development 69 Control of Morphogenesis in Hydra 72 Selected References 75 CHAPTER 6 Transmembrane Transport and the Control of Bioelectrical Activities 77 Classification of Transport Systems in Bacteria 78 Solute Facilitators 80 Chemically Driven Active Transport 81 Group Translocation Catalyzed by the Bacterial Phosphotransferase System 82 Regulation of Transport Function by the Membrane Potential and the Control of Bioelectric Activity 85 Evolution of Interrelated Metabolic Enzymes, Transport Proteins, Membrane Receptors, and Regulatory Proteins 89 Selected References 90 CHAPTER 7 Cell Surface Receptors, Second Messengers, and the Control of Cellular Activities 92 Mechanisms of Inter- and Intracellular Signal Transmission 92 Control of Carbohydrate Catabolic Enzyme Synthesis by Intracellular Inducer and Cyclic AMP 94 Coordinate Regulation of Adenylate Cyclase and Inducer Uptake by the Phosphotransferase System 95 Induction of Protein Synthesis by Extracellular Inducers 98 Selected References 102 CHAPTER 8 Mechanisms of Chemoreception, Electrical Signal Transduction, and Biological Response 103 Bacterial Chemotaxis: A Model of Sensation, Regulation, and Adaptation 103 Bacterial Chemoreceptors 107 The Avoidance Reaction of Paramecium 110 Ion Channels and Behavioral Mutants in Paramecium 114 Chemotactic Control of Behavior in Dictyostelium discoideum 116 Selected References 122 CHAPTER 9 Pheromone-Mediated Control of Sexual Activity 123 Control of Bacterial Conjugation by Sex Pheromones 124 Pheromone Control of Yeast Mating 125 Pheromone Control of Sexual Activities in Insects 129 Genetic Dissection of Courtship Behavior in Drosophila 131 Selected References 133Contents xv CHAPTER 10 Cellular Recognition: Mechanisms and Consequences of Homotypic and Heterotypic Adhesions 135 t Loci in Mice: Components of a Genetic Program for Embryonic Development 136 Cellular Recognition and Tissue Formation 137 Sexual Agglutination in Yeast 138 Developmental Control of Cellular Cohesion in Dictyostelium discoideum 143 Heterotypic Adhesion of Bacterial Viruses to Their Hosts and Phage- Mediated Receptor Conversion 147 Cell-Cell Contact as a Signal for Induction of Tissue-Specific Protein Biosynthesis 149 Contact Inhibition of Fibroblast Growth 150 Sea Urchin Egg Fertilization 151 Selected References 156 CHAPTER 11 Switch Mechanisms Regulating Gene Expression 158 Epigenetics in Animal Cells Maintained in Tissue Culture 158 DNA Methylation and the Control of Gene Expression in Animal Cells 160 Paramutation in Plants 161 Transposable Elements in Plants Controlling Gene Expression and Mutation Rate 163 Switch Mechanisms in Microorganisms 164 Biphasic Flagellar Phase Variation in Salmonella 166 Inversion of the G Segment in Phage Mu 168 Invertible and Transposable Elements in Differentiation 171 Selected References 172 CHAPTER 12 Sex Determination and the Interconversion of Mating Type 174 Sex Determination in Yeast 175 Mating Type Interconversion in Yeast 178 Pattern Control of Mating Type Switching 182 Sex Determination in Drosophila 184 Sexual Interconversion in Higher Plants and Animals 185 Selected References 186 CHAPTER 13 Genetic Control of Development, Mating Type Determination, and Programmed Death in Ciliated Protozoa 187 Genetics of Paramecium and Tetrahymena 188 Control of Gene Expression in Ciliates 190 Mating Type Determination in Ciliates 191xv i Contents Irreversible Mating Type Determination by DNA Excision 193 DNA Excision in Immunoglobulin Synthesis 195 Aging and Programmed Death in Ciliates 196 Selected References 200 CHAPTER 14 Conclusions and Perspectives 202 Index 209

Biologie