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Wu, Albert M. (Herausgeber)

The Molecular Immunology of Complex Carbohydrates-3 (Gebundene Ausgabe)

Reihe: Advances in Experimental Medicine and Biology 705

Springer-Verlag GmbH, Springer US, Juli 2011

809 S. - Sprache: Englisch - 247x167x53 mm

ISBN: 1441978763 EAN: 9781441978769

Based on the third symposium on "Molecular Immunology of Complex Carbohydrates," this text covers the latest in glycotopes, structures and functions of complex carbohydrates, recognition factors of lectins, biomolecular interactions and other glycosciences.This volume highlights the informative events of the Symposium on Molecular Immunology of Complex Carbohydrates III, held at the Institute of Biological Chemistry, Academia Sinica, on July 15-20, 2007, in Taipei, Taiwan.

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One of the most comprehensive handbooks on carbohydrate specificities of applied lectins and anti- carbohydrate monoclonal antibodies in the fieldA useful tool for researchers and beginners in the fields of immunology, biochemistry, cancer research, and structural biology for years to comeIncludes events from MICC-III and Workshop on Immunology and Disease


Part 1: Introduction to Glyco-Experiences Chp 1: Serendipity in Scientific Discoveries: Some Examples in GlycosciencesChp 2: My 30 Years Devotion to the N-linked Oligosaccharide Structures Part 2: Blood group ABH/Le-related antigensChp 3: Human Blood Group ABH/Ii, Lea, b, x, y and Sialyl Lea, x Glycotopes, Internal Structures and Immunochemical Roles of Human Ovarian Cyst GlycoproteinsChp 4: Lewis Glyco-Epitopes: Structure, Biosynthesis and FunctionsChp 5: An Unique Endo-¿-Galactosidase that Cleaves Both Blood Group A and B Glycotopes Part 3: Lectins      Chp 6: Recognition Intensities of Mammalian Structural Units, Ligand Clusters and Polyvalency in the Lectin-Glycan Interaction ProcessesChp 7: Adhesion/Growth-Regulatory Galectins: Insights into their Ligand Selectivity Using Natural Glycoproteins and GlycotopesChp 8: Glycotope Structures and Intramolecular Affinity Factors of Plant Lectins for Tn/T AntigensChp 9: The Five Bacterial Lectins (PA-IL, PA-IIL, RSL, RS-IIL and CV-IIL) - Interactions with Diverse Animal Cells and GlycoproteinsChp 10:       On the Differential Sialic Acid Specificity of Lectins from Different Parts of Saraca indicaChp 11:       Regulation of Lectin Production by the Human Pathogens Pseudomonas aeruginosa and Chromobacterium violaceum: Effects of Choline, Trehalose and EthanolChp 12:       Non-Carbohydrate Mediated Interaction of Lectins with Plant ProteinsChp 13:       Novel Concepts about the Role of Lectins in the Plant Cell Part 4: Structures and Functions of Glycolipids Chp 14:       Role of Gangliosides and of Plasma Membrane Associated Sialidase in the Process of Cell Membrane OrganizationChp 15:       9-O-Acetyl GD3 in Lymphoid and Erythroid CellsChp 16:       GM3 Up-Regulation of Matrix Metalloproteinase-9 (MMP-9) Possibly through PI3K, AKT, RICTOR, RhoGDI-2 and TNF-a Pathways in Mouse Melanoma B16 CellsChp 17:       Pathological Roles of Ganglioside Mimicry in Guillain-Barré Syndrome and Related NeuropathiesChp 18:       Structure and Function of Glycolipids in Thermophilic BacteriaChp 19:       Lipooligosaccharides (LOSs) of Neisseria Species: Similarity between N. Polysaccharea and N. Meningitidis LOSs Part 5: Structures and Functions of Complex Carbohydrates     Chp 20:       Roles for N- and O-Glycans in Early Mouse DevelopmentChp 21:       Glycobiology in the Field of Gerontology (Glycogerontology)Chp 22:       Galectins in Regulation of ApoptosisChp 23:       Avian and Human Influenza Virus Receptors and their DistributionChp 24:       Importance of a Factor VIIIc-Like Glycoprotein Expressed in Capillary Endothelial Cells (eFactor VIIIc) in AngiogenesisChp 25:       Mucin O-Glycan Branching Enzymes: Structure, Function and Gene RegulationChp 26:       Studying the Carbohydrate Self-Recognition in Marine Sponges Using Synthetic Aggregation Factor EpitopesChp 27:       Docking of Chitin Oligomers and Nod Factors on LysM Lectin Domains of the LysM-RLK Receptors as a First Recognition Step for the Establishment of the Medicago truncatula-Rhizobium Symbiosis Part 6: Glyco-Immunology   Chp 28:       O-Acetylated Sialic Acids and their Role in Immune DefenceChp 29:       Sialylated and Sulfated Carbohydrate Ligands for Selectins and Siglecs - Involvement in Traffic and Homing of Human Memory T- and B- LymphocytesChp 30:       Diversity of Natural Anti-¿-Galactosyl Antibodies in Human SerumChp 31:       Prospective Highlights of Serum Glycoprotein Profiles in Spontaneous Tolerance after Liver Allograft Transplantation Part 7: Glycobiology of Cancer    Chp 32:       Hematogenous Metastasis: Roles of CD44v and Alternative Sialofucosylated Selectin LigandsChp 33:       Regulation of Glycosyltransferase Genes in Apoptotic Breast Cancer Cells Induced by L-PPMP and cis-PlatinChp 34:       Aberrant Glycosphingolipid Expression and Membrane Organization in Tumor Cells. Consequences on Tumor-Host InteractionsChp 35:       Human KDN (Deaminated Neuraminic Acid) and its Elevated Expression in Cancer Cells - Mechanism and SignificanceChp 36:       Polysialic Acid Bioengineering of Cancer and Neuronal Cells by N-Acyl Sialic Acid Precursor Treatment Part 8: Glyco-Applications Chp 37:       Synthesis of Hemagglutinin-Binding TrisaccharidesChp 38:       Fabrication and Applications of Glyco-NanomaterialsChp 39:       Glycan Arrays to Decipher the Specificity of Plant LectinsChp 40:       Targeting C-Type Lectin for the Treatment of Flavivirus Infections APPENDIX      INDEX

Über den Autor

Dr. Wu has been studying on lectin-glycan interactions for more than 35 years, especially the recognition factors of lectins. He is the senior editor of the Molecular Immunology of Complex Carbohydrates 1 and 2 (Adv. Exp. Med. Biol. 228 and 491). Lectin recognition index is his ongoing project.

ISBN 1-441978-76-3, ISBN 1-44-197876-3, ISBN 1-44197-876-3, ISBN 1-441-97876-3, ISBN 1-4419-7876-3

ISBN 978-1-441978-76-9, ISBN 978-1-44-197876-9, ISBN 978-1-44197-876-9, ISBN 978-1-441-97876-9, ISBN 978-1-4419-7876-9

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