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Poupon, Erwan (Herausgeber); Nay, Bastien (Herausgeber)

Biomimetic Organic Synthesis. 2 volumes (Gebundene Ausgabe)

Wiley VCH Verlag GmbH, Wiley-VCH Verlag GmbH & Co. KGaA, April 2011

956 S. - Sprache: Englisch - 247x182x56 mm Subskriptionspreis

ISBN: 3527325808 EAN: 9783527325801

A comprehensive treatment, in two volumes, of the approach and methodology of bio-inspired synthesis of complex natural products, including alkaloids, terpenes, polyketides, and polyphenols.

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VOLUME 1 PART I BIOMIMETIC TOTAL SYNTHESIS OF ALKALOIDS Biomimetic Synthesis of Ornithine/Arginine and Lysine-Derived Alkaloids: Selected Examples Biomimetic Synthesis of Alkaloids Derived from Tyrosine: The Case of FR-901483 and TAN-1251 Compounds Biomimetic Synthesis of Alkaloids Derived from Tryptophan: Indolemonoterpene Alkaloids Biomimetic Synthesis of Alkaloids Derived from Tryptophan: Dioxopiperazine Alkaloids Biomimetic Synthesis of Alkaloids with a Modified Indole Nucleus Biomimetic Synthesis of Manzamine Alkaloids Biomimetic Synthesis of Marine Pyrrole-2-Aminoimidazole and Guanidinium Alkaloids Biomimetic Syntheses of Alkaloids with a Non-Amino Acid Origin Biomimetic Synthesis of Azole- and Aryl-Peptide Alkaloids Biomimetic Synthesis of Indole-Oxidized and Complex Peptide Alkaloids VOLUME 2 PART II BIOMIMETIC SYNTHESIS OF TERPENOIDS AND POLYPRENYLATED NATURAL COMPOUNDS Biomimetic Rearrangements of Complex Terpenoids Polyprenylated Phloroglucinols and Xanthones PART III BIOMIMETIC SYNTHESIS OF POLYKETIDES Polyketide Assembly Mimics and Biomimetic Access to Aromatic Rings Biomimetic Synthesis of Non-Aromatic Polycyclic Polyketides Biomimetic Synthesis of Polyether Natural Products via Polyepoxide Opening Biomimetic Electrocyclization Reactions toward Polyketide-Derived Natural Products PART IV BIOMIMETIC SYNTHESIS OF POLYPHENOLS Biomimetic Synthesis and Related Reactions of Ellagitannins Biomimetic Synthesis of Lignans Synthetic Approaches to the Resveratrol-Based Family of Oligomeric Natural Products Sequential Reactions Initiated by Oxidative Dearomatization. Biomimicry or Artifact? PART V FRONTIERS IN BIOMIMETIC CHEMISTRY: FROM BIOLOGICAL TO BIO-INSPIRED PROCESSES The Diels?Alderase Never Ending Story Bio-Inspired Transfer Hydrogenations Life?s Single Chirality: Origin of Symmetry Breaking in Biomolecules PART VI CONCLUSION: FROM NATURAL FACTS TO CHEMICAL FICTIONS Artifacts and Natural Substances Formed Spontaneously

Über den Autor

Erwan Poupon is a pharmacist, he obtained his PhD in organic chemistry under the supervision of Dr. Nicole Kunesch and Prof. Henri-Philippe Husson in 2000 at Paris-Descartes University. He was subsequently a post-doctoral fellow at the University of California at San Diego working with Prof. Emmanuel Theodorakis. He then joined the faculty at the School of Pharmacy of Paris-Sud University where he is now Professor of pharmacognosy and natural product chemistry. His fields of interest relate to the chemistry of natural products, including biomimetic synthesis and chemical biology. Bastien Nay obtained his diploma of Pharmacy in 1998 and his PhD in organic chemistry in 2000 under the guidance of Prof. Joseph Vercauteren at the School of Pharmacy of Bordeaux, France. He then joined Prof. J. Stephen Clark's group as a post-doctoral fellow at the University of Nottingham, UK. In 2003 he was appointed research scientist at the CNRS, now working and teaching at the National Museum of Natural History in Paris, where he is managing the natural product chemistry team. His research interests non only concern the synthetic strategies towards natural products, but also their origin and raion d'?tre.


"The volumes will be widely acclaimed as an important, meticulously researched and engagingly presented contribution unrivalled in comprehensiveness and quality ... A single most thoroughly self-consistent and comprehensively inspiring work that will ensure the continued development in an exciting field." (Current Engineering Practice, 2011)

ISBN 3-527-32580-8

ISBN 978-3-527-32580-1

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